儿童胃食管反流和健康儿童的胃排空。

Gastric emptying in children with gastroesophageal reflux and in healthy children.

机构信息

Faculty of Medicine, University of Oslo, 0316 Oslo, Norway; Department of Pediatric Surgery, Oslo University Hospital Rikshospitalet, 0424 Oslo, Norway.

出版信息

J Pediatr Surg. 2013 Sep;48(9):1856-61. doi: 10.1016/j.jpedsurg.2013.03.076.

DOI:10.1016/j.jpedsurg.2013.03.076

PMID:24074657

Abstract

PURPOSE

The aim of this report is to examine whether children with gastroesophageal reflux (GER) have delayed gastric emptying compared to healthy children.

METHODS

All patients had GER verified by 24-hour pH monitoring. Gastric emptying of cow's milk was examined by radionuclide scintigraphy in 51 patients with GER and in 24 controls. Gastric emptying rate was expressed as exponential half time (T1/2).

RESULTS

Median age was 4.4 years [range 0.1-15.4] in patients and 6.1 years [range 2.5-10.0] in controls (p=.10). A wide range of gastric emptying rates was observed both in GER patients [range 16-121] and controls [range 29-94]. One GER patient (2%) had slower gastric emptying (T1/2=121 min) than the healthy child with the longest T1/2 (94 min). Mean T1/2 was 49 minutes (SD 20.1) and 46 minutes (SD 14.2) in GER patients and controls, respectively (p=.51).

CONCLUSIONS

Gastric emptying rate of milk was not significantly different between children with GER and healthy children. A wide range of gastric emptying rates was observed in both groups.

摘要

目的

本报告旨在研究胃食管反流（GER）患儿与健康儿童相比是否存在胃排空延迟。

方法

所有患者均通过 24 小时 pH 监测证实存在 GER。51 例 GER 患儿和 24 例对照患儿均通过放射性核素闪烁扫描检查牛奶奶液的胃排空情况。胃排空率以指数半排空时间（T1/2）表示。

结果

患儿的中位年龄为 4.4 岁[范围 0.1-15.4]，对照组为 6.1 岁[范围 2.5-10.0]（p=.10）。GER 患儿[范围 16-121]和对照组[范围 29-94]的胃排空率差异较大。1 例 GER 患儿（2%）的胃排空速度较慢（T1/2=121 分钟），低于健康儿童中 T1/2 最长的儿童（94 分钟）。GER 患儿和对照组的平均 T1/2 分别为 49 分钟（SD 20.1）和 46 分钟（SD 14.2）（p=.51）。