Department of Pediatric Surgery, Erasmus MC - Sophia Children's Hospital, Rotterdam, The Netherlands; Department of Surgery - Pediatric Surgery, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands.
J Pediatr Surg. 2013 Sep;48(9):1914-8. doi: 10.1016/j.jpedsurg.2013.04.025.
It has been suggested that the outcome of transanal endorectal pull-through for classic Hirschprung's disease can be improved by laparoscopically mobilizing the colon before the pullthrough.
Charts of 43 patients (2005-2009) with proven recto-sigmoid aganglionosis were retrospectively analyzed with respect to postoperative outcomes. Twenty-one had been treated with the transanal endorectal pull through (TERPT) and 22 with the laparoscopically assisted TERPT (LTERPT).
Gender ratio, congenital anomalies, preoperative enterostomy, and follow up did not differ between the groups. More colon was resected in the TERPT group: median 25 cm vs. 15 cm in the L-TERPT group (p<0.001). The TERPT-procedure took less time: median 153 min. vs. L-TERPT 263 min (p<0.001). Postoperatively, three patients showed colonic torsions after TERPT (p=0.07). The long-term clinical outcomes did not differ significantly between both groups. There was a significant association between length of resection and obstructive symptoms (OR=0.92, p=0.01).
Postoperative and clinical outcomes are similar using the TERPT or L-TERPT to correct classic segment Hirschsprung's disease. Prevention of colonic torsion should be the prime concern during the TERPT procedure. L-TERPT requires laparoscopic equipment and takes more operation time, whereas TERPT leaves no visible scars. The positive relation between the larger length of resection and obstructive symptoms requires additional research.
有研究表明,在经肛门直肠内拖出术(TERPT)前通过腹腔镜游离结肠可改善经典型先天性巨结肠的治疗效果。
回顾性分析了 43 例经直肠乙状结肠活检证实为直肠乙状结肠无神经节细胞症患者的临床资料,比较了经肛门直肠内拖出术(TERPT)和腹腔镜辅助经肛门直肠内拖出术(L-TERPT)的术后结果。
两组患者的性别比例、先天性异常、术前肠造口和随访时间无显著差异。TERPT 组切除的结肠更多:中位数 25cm 比 L-TERPT 组 15cm(p<0.001)。TERPT 组手术时间更短:中位数 153 分钟比 L-TERPT 组 263 分钟(p<0.001)。术后,有 3 例 TERPT 后出现结肠扭转(p=0.07)。两组患者的长期临床结局无显著差异。切除长度与梗阻症状显著相关(OR=0.92,p=0.01)。
经肛门直肠内拖出术(TERPT)或腹腔镜辅助经肛门直肠内拖出术(L-TERPT)治疗经典型先天性巨结肠的术后和临床结局相似。在 TERPT 手术中,应注意预防结肠扭转。L-TERPT 需要腹腔镜设备,且手术时间更长,而 TERPT 术后无明显疤痕。切除长度与梗阻症状之间的正相关关系需要进一步研究。