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飞秒激光辅助白内障手术中囊膜切开的扫描电子显微镜评估。

Scanning electron microscopy evaluation of capsulorhexis in femtosecond laser-assisted cataract surgery.

机构信息

From the Ophthalmology Clinic (L. Mastropasqua, Toto, Calienno, Mattei, Vecchiarino), Department of Medicine and Science of Ageing, and the Department of Medical, Oral, and Biotechnological Science (Di Iorio), University G. D'Annunzio Chieti-Pescara, Chieti, and the Ophthalmic Clinic (A. Mastropasqua), Campus Biomedico, University of Rome, Rome, Italy.

出版信息

J Cataract Refract Surg. 2013 Oct;39(10):1581-6. doi: 10.1016/j.jcrs.2013.06.016.

DOI:10.1016/j.jcrs.2013.06.016
PMID:24075159
Abstract

PURPOSE

To use scanning electron microscopy (SEM) to evaluate capsulorhexis-cut quality obtained during femtosecond laser-assisted cataract surgery at different energy settings and evaluate whether there are differences between this technique and a standard manual technique.

SETTING

Ophthalmology Clinic, Department of Medicine and Science of Ageing, University G. D'Annunzio Chieti-Pescara, Chieti, Italy.

DESIGN

Prospective nonrandomized single blinded study.

METHODS

Sixty capsulorhexes obtained using the conventional manual technique and the femtosecond laser with different laser energy settings were divided into 5 groups as follows: Group 1 (12 capsulorhexes) obtained with the manual technique and Groups 2 to 5 (each with 12 capsulorhexes) obtained with the femtosecond laser at 7.0 μJ, 13.5 μJ, 14.0 μJ, and 15.0 μJ, respectively. All samples were evaluated using SEM to compare the thickness along the capsulorhexis edge and the overall irregularity of the cut surface.

RESULTS

Capsulorhexes obtained with the femtosecond laser at all energy settings were perfectly circular with negligible deformation. Group 1 and Group 2 had a significantly higher thickness and lower thickness, respectively, of the capsulorhexis edge than the other 3 groups (P<.001). There was also a statistically significant correlation between the degree of irregularity and increasing energy (P<.001).

CONCLUSIONS

The use of the femtosecond laser in cataract surgery resulted in better capsulorhexis geometry and circularity than the manual capsulorhexis. The cut surface was smoother in the manual group. In the femtosecond laser groups, the degree of irregularity was higher at increasing energy settings.

FINANCIAL DISCLOSURE

No author has a financial or proprietary interest in any material or method mentioned.

摘要

目的

使用扫描电子显微镜(SEM)评估飞秒激光辅助白内障手术中不同能量设置下获得的囊膜环形撕囊质量,并评估该技术与标准手动技术之间是否存在差异。

设置

意大利切塞纳-佩斯卡拉大学医学与衰老科学系眼科诊所。

设计

前瞻性非随机单盲研究。

方法

将使用传统手动技术和不同激光能量设置的飞秒激光获得的 60 个囊膜环形撕囊分为 5 组:第 1 组(12 个囊膜环形撕囊)使用手动技术,第 2 组至第 5 组(每组 12 个囊膜环形撕囊)分别使用飞秒激光在 7.0 μJ、13.5 μJ、14.0 μJ 和 15.0 μJ 下获得。所有样本均使用 SEM 进行评估,以比较囊膜环形撕囊边缘的厚度和切割表面的整体不规则性。

结果

在所有能量设置下使用飞秒激光获得的囊膜环形撕囊均为完美圆形,几乎没有变形。第 1 组和第 2 组的囊膜环形撕囊边缘的厚度明显更高和更低,分别与其他 3 组相比(P<.001)。不规则程度与能量增加之间也存在统计学上的显著相关性(P<.001)。

结论

飞秒激光在白内障手术中的应用导致囊膜环形撕囊的几何形状和圆形度优于手动囊膜环形撕囊。手动组的切割表面更光滑。在飞秒激光组中,不规则程度随着能量设置的增加而增加。

财务披露

没有作者在任何提到的材料或方法中拥有财务或所有权利益。

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