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乳腺癌分期、社会阶层与筛查的影响。

Breast cancer stage, social class and the impact of screening.

作者信息

Roberts M M, Alexander F E, Elton R A, Rodger A

机构信息

Edinburgh Breast Screening Centre.

出版信息

Eur J Surg Oncol. 1990 Feb;16(1):18-21.

PMID:2407559
Abstract

Two studies were carried out to examine socio-economic factors in breast cancer: a random sample of all new cases in Edinburgh in 1979 was reviewed, and the control population of the Edinburgh randomized trial of breast screening was used to determine stage and survival in relation to social class. Small area statistics from census data were used as measures of social class, the method being now well accepted. More than one-third of women still present with obviously advanced or metastatic breast cancer, but both studies showed this has no association with socio-economic status. Late stage at presentation is a serious problem, and although mass screening is likely to cause an improvement in those who are screened, it cannot in those who do not attend for screening. As attendance is related to social class, less affluent women are less likely to benefit and will continue to be diagnosed with advanced disease.

摘要

开展了两项研究以调查乳腺癌的社会经济因素

对1979年爱丁堡所有新病例的随机样本进行了回顾,并利用爱丁堡乳腺癌筛查随机试验的对照人群来确定与社会阶层相关的分期和生存率。来自人口普查数据的小区域统计数据被用作社会阶层的衡量指标,该方法目前已被广泛接受。超过三分之一的女性仍表现为明显晚期或转移性乳腺癌,但两项研究均表明这与社会经济地位无关。就诊时处于晚期是一个严重问题,尽管大规模筛查可能会使接受筛查的人群情况得到改善,但对未参加筛查的人群则无作用。由于就诊率与社会阶层有关,较贫困的女性受益可能性较小,仍会被诊断为晚期疾病。

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引用本文的文献

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The late-stage diagnosis of colorectal cancer: demographic and socioeconomic factors.结直肠癌的晚期诊断:人口统计学和社会经济因素
Am J Public Health. 1996 Dec;86(12):1794-7. doi: 10.2105/ajph.86.12.1794.
2
Locally advanced breast cancer: report of phase II study and subsequent phase III trial.局部晚期乳腺癌:II期研究及后续III期试验报告
Br J Cancer. 1992 May;65(5):761-5. doi: 10.1038/bjc.1992.160.
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Stage at diagnosis in breast cancer: race and socioeconomic factors.乳腺癌诊断时的分期:种族与社会经济因素
Am J Public Health. 1992 Oct;82(10):1383-5. doi: 10.2105/ajph.82.10.1383.
4
Management of breast cancer.乳腺癌的管理
BMJ. 1992 Jul 11;305(6845):113. doi: 10.1136/bmj.305.6845.113-c.