Mandelblatt J, Andrews H, Kao R, Wallace R, Kerner J
Memorial Sloan-Kettering Cancer Center, Department of Epidemiology and Biostatistics, New York, NY, USA.
Am J Public Health. 1996 Dec;86(12):1794-7. doi: 10.2105/ajph.86.12.1794.
This study described factors related to colorectal cancer stage at diagnosis.
Logistic regression analyses were used on data from the New York State Tumor Registry and US Census area-level social class indicators.
After the effects of other predictors were controlled for, the odds of late-stage cancer increased as age decreased; women and African Americans were significantly more likely to have late stage than men and Whites; and individuals living in areas of low socioeconomic status (SES) were significantly more likely to be diagnosed at late stage than those living in higher SES areas. Stratified analyses showed that living in a low SES area was the most important determinant of stage for all age, race, gender and source-of-care groups.
While all populations would benefit from the systematic use of screening socioeconomically disadvantaged groups may also benefit from targeted screening.
本研究描述了与结直肠癌诊断分期相关的因素。
对来自纽约州肿瘤登记处的数据和美国人口普查区域层面的社会阶层指标进行逻辑回归分析。
在控制了其他预测因素的影响后,癌症晚期的几率随着年龄的降低而增加;女性和非裔美国人比男性和白人更有可能处于晚期;与生活在社会经济地位较高地区的人相比,生活在社会经济地位较低(SES)地区的人被诊断为晚期的可能性显著更高。分层分析表明,生活在低SES地区是所有年龄、种族、性别和医疗来源组分期的最重要决定因素。
虽然所有人都能从系统性筛查中受益,但社会经济弱势群体可能也会从针对性筛查中受益。