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轻度盆腔子宫内膜异位症不孕患者三种治疗方式的比较

Comparison of three modes of treatment for infertility patients with minimal pelvic endometriosis.

作者信息

Chong A P, Keene M E, Thornton N L

机构信息

Department of Obstetrics and Gynecology, Mount Sinai Hospital, Hartford, Connecticut.

出版信息

Fertil Steril. 1990 Mar;53(3):407-10. doi: 10.1016/s0015-0282(16)53331-7.

DOI:10.1016/s0015-0282(16)53331-7
PMID:2407563
Abstract

Minimal pelvic endometriosis can be the only pathology found in infertility patients undergoing an infertility work-up. Although the mechanism by which endometriosis causes infertility is not known, it is well established that pregnancy can be attained in many patients when this disease is treated. Three different modes of treatment were used in 167 infertility patients who had minimal pelvic endometriosis without other pelvic pathology. Group I (danazol) achieved 48.9% pregnancy rates (23/47), group II (CO2 laser) had 44.6% pregnancy rates (37/83), and group III (CO2 laser and danazol) achieved 51.4% pregnancy rates (19/37). Although the pregnancy rates in groups I and III were higher, they were not statistically significant when compared with group II.

摘要

轻度盆腔子宫内膜异位症可能是接受不孕症检查的患者中唯一发现的病理情况。虽然子宫内膜异位症导致不孕的机制尚不清楚,但众所周知,这种疾病得到治疗后,许多患者能够怀孕。167例患有轻度盆腔子宫内膜异位症且无其他盆腔病变的不孕症患者采用了三种不同的治疗方式。第一组(达那唑)的妊娠率为48.9%(23/47),第二组(二氧化碳激光)的妊娠率为44.6%(37/83),第三组(二氧化碳激光加达那唑)的妊娠率为51.4%(19/37)。虽然第一组和第三组的妊娠率较高,但与第二组相比,差异无统计学意义。

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Comparison of three modes of treatment for infertility patients with minimal pelvic endometriosis.轻度盆腔子宫内膜异位症不孕患者三种治疗方式的比较
Fertil Steril. 1990 Mar;53(3):407-10. doi: 10.1016/s0015-0282(16)53331-7.
2
CO2 laser laparoscopy for the treatment of endometriosis associated with infertility.二氧化碳激光腹腔镜手术治疗与不孕相关的子宫内膜异位症。
J Reprod Med. 1985 May;30(5):409-12.
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Combined laparoscopic surgery and danazol therapy for pelvic endometriosis.腹腔镜手术联合达那唑治疗盆腔子宫内膜异位症。
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Danazol versus carbon dioxide laser plus postoperative danazol: treatment of infertility due to mild pelvic endometriosis.
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Efficacy of isotopic 13CO2 laser laparoscopic evaporation in the treatment of infertile patients with minimal and mild endometriosis: a life table cumulative pregnancy rates study.同位素13CO2激光腹腔镜汽化术治疗轻度和中度子宫内膜异位症不孕患者的疗效:一项生命表累积妊娠率研究
J Am Assoc Gynecol Laparosc. 1997 Feb;4(2):219-23. doi: 10.1016/s1074-3804(97)80013-8.
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Comparison of different treatment modalities of endometriosis in infertile women.子宫内膜异位症不同治疗方式对不孕女性的疗效比较。
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Life table analysis of pregnancy rates in women with moderate or severe endometriosis comparing danazol therapy after carbon dioxide laser laparoscopy plus electrocoagulation or laparotomy plus electrocoagulation versus danazol therapy only.
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Medical versus surgical treatment of endometriosis.子宫内膜异位症的药物治疗与手术治疗
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Medical treatment of endometriosis in infertile patients.不孕患者子宫内膜异位症的医学治疗。
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引用本文的文献

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The effectiveness of reproductive surgery in the treatment of female infertility: facts, views and vision.生殖手术治疗女性不孕症的有效性:事实、观点与展望。
Facts Views Vis Obgyn. 2010;2(4):232-52.
2
The treatment of mild endometriosis with laser laparoscopy: a two-step treatment analysis of patients whose primary therapy was successful.激光腹腔镜治疗轻度子宫内膜异位症:对初始治疗成功患者的两步治疗分析
JSLS. 2006 Jan-Mar;10(1):30-6.