Center for Health Care Evaluation, VA Palo Alto Health Care System (152MPD), 795 Willow Rd., Menlo Park, CA 94025, USA.
J Subst Abuse Treat. 2014 Feb;46(2):87-97. doi: 10.1016/j.jsat.2013.08.022. Epub 2013 Sep 26.
Given the often chronic nature of substance use disorders, patients sometimes receive less intensive continuing care following an initial period of more intensive treatment. This meta-analysis estimated the effect of continuing care and formally tested several proposed moderators (intervention duration, intensity, modality, and setting) of that effect. A systematic search identified 33 controlled trials of continuing care; 19 included a no/minimal treatment condition and were analyzed to assess the overall effect of continuing care versus control. Continuing care had a small, but significant, positive effect size, both at the end of the continuing care interventions (g=0.187, p<0.001) and at follow-up (g=0.271, p<0.01). Limited by a small number of studies, analyses did not identify any significant moderators of overall effects. These results show that continuing care can provide at least modest benefit after initial treatment. We discuss study characteristics that may have reduced the magnitude of the overall continuing care effect estimate.
鉴于物质使用障碍的慢性性质,患者在接受初始强化治疗后,有时会接受较少的强化持续护理。本荟萃分析评估了持续护理的效果,并正式检验了该效果的几个拟议调节因素(干预持续时间、强度、模式和环境)。系统搜索确定了 33 项持续护理的对照试验;其中 19 项研究包含无/最低治疗条件,并进行了分析,以评估持续护理与对照的总体效果。持续护理具有较小但显著的积极效果大小,无论是在持续护理干预结束时(g=0.187,p<0.001)还是在随访时(g=0.271,p<0.01)。由于研究数量有限,分析未发现任何对总体效果有显著影响的调节因素。这些结果表明,在初始治疗后,持续护理至少可以提供适度的益处。我们讨论了可能降低总体持续护理效果估计值的研究特征。