University of Waterloo, 200 University Avenue West, Waterloo, Ontario, Canada N2L3G1.
Neuropsychologia. 2013 Nov;51(13):2526-33. doi: 10.1016/j.neuropsychologia.2013.09.024. Epub 2013 Sep 25.
We investigated how right hemisphere lesions affected location priming and statistical learning in four groups of participants: young controls, older controls, and right brain damaged patients with or without spatial neglect. Using a version of the Maljkovic and Nakayama's (1994) priming task, but with all the targets presented at the mid-line, we biased the transition probability for targets to repeat their spatial location. The decrease in response time with spatial repetition allowed us to quantify priming, and the modulation of priming strength as a function of repeat probability allowed us to assess for statistical learning. Contrary to the healthy controls, right brain damage decreased (but did not abolish) spatial priming. Right brain damaged patients did not modulate the magnitude of the spatial priming effect with variation in repeat frequency, as did the control groups. We conclude that damage to the right hemisphere impairs spatial priming and that priming impairment co-exists with, and may contribute to an inability to learn environmental statistical regularities. Such deficits could contribute to functional deficits and a poorer response to rehabilitation.
年轻的对照组，老年对照组，和右脑损伤患者与或没有空间忽视。使用 Maljkovic 和 Nakayama（1994）的启动任务的一个版本，但所有的目标都在中线呈现，我们偏向于目标重复其空间位置的转移概率。随着空间重复的响应时间的减少，我们可以量化启动，并且启动强度随重复概率的调制允许我们评估统计学习。与健康对照组相反，右脑损伤降低了（但没有消除）空间启动。右脑损伤患者没有随着重复频率的变化来调节空间启动效应的幅度，就像对照组一样。我们得出结论，右半球损伤会损害空间启动，而启动损伤与无法学习环境统计规律并存，并可能导致功能障碍和对康复反应较差。这些缺陷可能导致功能障碍和对康复的反应较差。
