Biocomputing Unit, National Center for Biotechnology (CSIC), c/Darwin, 3, Campus Universidad Autónoma, 28049 Cantoblanco, Madrid, Spain; Escuela Politécnica Superior, Universidad Autónoma de Madrid, Campus Universidad Autónoma, 28049 Cantoblanco, Madrid, Spain.
J Struct Biol. 2013 Nov;184(2):321-8. doi: 10.1016/j.jsb.2013.09.015. Epub 2013 Sep 26.
Xmipp is a specialized software package for image processing in electron microscopy, and that is mainly focused on 3D reconstruction of macromolecules through single-particles analysis. In this article we present Xmipp 3.0, a major release which introduces several improvements and new developments over the previous version. A central improvement is the concept of a project that stores the entire processing workflow from data import to final results. It is now possible to monitor, reproduce and restart all computing tasks as well as graphically explore the complete set of interrelated tasks associated to a given project. Other graphical tools have also been improved such as data visualization, particle picking and parameter "wizards" that allow the visual selection of some key parameters. Many standard image formats are transparently supported for input/output from all programs. Additionally, results have been standardized, facilitating the interoperation between different Xmipp programs. Finally, as a result of a large code refactoring, the underlying C++ libraries are better suited for future developments and all code has been optimized. Xmipp is an open-source package that is freely available for download from: http://xmipp.cnb.csic.es.
Xmipp 是一款专门用于电子显微镜图像处理的软件包，主要专注于通过单颗粒分析对大分子进行 3D 重建。在本文中，我们介绍了 Xmipp 3.0，这是一个主要版本，相对于上一个版本有了几个改进和新的发展。一个核心改进是项目的概念，它存储了从数据导入到最终结果的整个处理工作流程。现在可以监控、重现和重新启动所有计算任务，并以图形方式探索与给定项目相关的整套相互关联的任务。其他图形工具也得到了改进，例如数据可视化、颗粒选择和参数“向导”，它们允许对一些关键参数进行可视化选择。许多标准图像格式都可以透明地支持所有程序的输入/输出。此外，结果已经标准化，便于不同 Xmipp 程序之间的互操作。最后，由于大量的代码重构，底层 C++库更适合未来的发展，并且所有代码都进行了优化。Xmipp 是一个开源软件包，可以从以下网址免费下载：http://xmipp.cnb.csic.es。
