aDepartment of Cardiac Sciences, LIBIN Cardiovascular Institute of Alberta, University of Calgary, Calgary, Alberta, Canada bDepartment of Cardiothoracic Surgery, Erasmus University Medical Center, Rotterdam, the Netherlands.
Curr Opin Cardiol. 2013 Nov;28(6):646-53. doi: 10.1097/HCO.0000000000000001.
Arterial grafting is superior to venous grafting in coronary artery bypass graft surgery with respect to graft patency and long-term patient outcome, but it may be difficult to achieve complete arterial revascularization.
Use of arterial grafts, especially bilateral internal mammary artery grafts, is not common, whereas there are clear indications that it may increase survival. Definitions of complete revascularization are varied and confusing, making study comparisons difficult. Technical challenges in complete revascularization with arterial grafts can be minimized by surgical techniques. Competitive flow in moderately stenosed coronary arteries grafted with arterial conduits may result in reduced patency. While internal mammary arteries may be used in arteries with at least 60% stenosis, radial artery and gastroepiploic grafts are best placed onto coronaries with severe stenosis. Moderate lesions in the left coronary circulation should be bypassed, but right coronary artery lesions can be left untouched as there is minimal progression over time. Complete revascularization may not be necessary or possible in every patient because of technical challenges.
Complete revascularization with arterial grafts presents both technical and physiological challenges. However, with techniques to maximize length of arterial conduits, knowledge of competitive flow and which moderate lesions should be addressed, complete revascularization with arterial grafts can be accomplished in the majority of patients, notwithstanding it may not be possible or even indicated for every patient.
在冠状动脉旁路移植术中,动脉移植物优于静脉移植物,在通畅率和长期患者预后方面均有优势,但可能难以实现完全的动脉血运重建。
尽管使用动脉移植物(尤其是双侧内乳动脉移植物)并不常见,但明确的适应证表明其可能会提高生存率。完全血运重建的定义多种多样且令人困惑,使得研究比较变得困难。通过手术技术可以最大限度地减少完全血运重建中动脉移植物的技术挑战。在中度狭窄的冠状动脉中使用动脉移植物可能会导致血流竞争,从而降低通畅率。内乳动脉可用于至少 60%狭窄的动脉,但桡动脉和胃网膜动脉移植物最好放置在严重狭窄的冠状动脉上。左冠状动脉循环中的中度病变应进行旁路移植,但右冠状动脉病变可以不处理,因为随着时间的推移病变进展极小。由于技术挑战,并非每个患者都需要或可能进行完全血运重建。
使用动脉移植物进行完全血运重建既存在技术挑战,也存在生理挑战。然而,通过最大化动脉移植物长度的技术、了解血流竞争以及确定需要处理哪些中度病变,大多数患者都可以实现完全血运重建,尽管对于某些患者来说,可能不可能或甚至不适合进行完全血运重建。