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肺炎球菌疫苗接种:争议与机遇

Pneumococcal vaccination. Controversies and opportunities.

作者信息

Spika J S, Fedson D S, Facklam R R

机构信息

Bureau of Communicable Disease Epidemiology, Laboratory Centre for Disease Control, Ottawa, Ontario, Canada.

出版信息

Infect Dis Clin North Am. 1990 Mar;4(1):11-27.

PMID:2407776
Abstract

The morbidity and mortality associated with pneumococcal infections are preventable in many high-risk individuals by immunization with 23-valent pneumococcal vaccine. While the clinical effectiveness of the current vaccine is less than ideal, use of the vaccine is cost effective. In spite of recommendations for pneumococcal vaccination of elderly and other high-risk persons, and federal reimbursement for vaccination Medicare enrollees, it was estimated in 1985 that only 10% to 15% of this target population was immunized. Strategies for immunizing high-risk individuals with pneumococcal vaccine need to involve physicians, public health professionals, health advocacy groups, and persons in the targeted populations.

摘要

对于许多高危个体而言,通过接种23价肺炎球菌疫苗可预防与肺炎球菌感染相关的发病率和死亡率。虽然目前疫苗的临床效果不尽理想,但使用该疫苗具有成本效益。尽管有针对老年人和其他高危人群接种肺炎球菌疫苗的建议,且联邦政府为医疗保险参保者的疫苗接种提供报销,但据1985年估计,该目标人群中只有10%至15%的人接种了疫苗。为高危个体接种肺炎球菌疫苗的策略需要医生、公共卫生专业人员、健康倡导团体以及目标人群中的个体共同参与。

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引用本文的文献

1
Efficacy of 23-valent pneumococcal vaccine in preventing pneumonia and improving survival in nursing home residents: double blind, randomised and placebo controlled trial.23 价肺炎球菌疫苗预防养老院居民肺炎和提高生存率的效果:双盲、随机、安慰剂对照试验。
BMJ. 2010 Mar 8;340:c1004. doi: 10.1136/bmj.c1004.
2
Practice guidelines for the management of community-acquired pneumonia in adults. Infectious Diseases Society of America.成人社区获得性肺炎管理实践指南。美国传染病学会。
Clin Infect Dis. 2000 Aug;31(2):347-82. doi: 10.1086/313954. Epub 2000 Sep 7.
3
Cost-effectiveness analysis of pneumococcal vaccination of adults and elderly persons in Belgium.
比利时成人和老年人肺炎球菌疫苗接种的成本效益分析。
Pharmacoeconomics. 2000 Jun;17(6):591-601. doi: 10.2165/00019053-200017060-00005.
4
Chronic obstructive pulmonary disease.慢性阻塞性肺疾病
Lancet. 1998 Aug 8;352(9126):467-73. doi: 10.1016/S0140-6736(97)11081-9.