Fiebach N, Beckett W
Section of General Internal Medicine, Yale University School of Medicine, New Haven, Conn.
Arch Intern Med. 1994 Nov 28;154(22):2545-57.
Influenza and pneumococcal infections are important causes of hospitalization and death among individuals who are elderly or who have chronic illnesses. Influenza and pneumococcal vaccines may prevent these infections and their complications, but most high-risk patients have not received them. Doubts about their effectiveness, fears of side effects, and the lack of programs to promote their use contribute to the underuse of these vaccines. Although adequate controlled trials in high-risk patients are lacking, there is observational evidence that they are moderately effective, reducing serious complications of influenza and pneumococcal infections by about one-half. They are cost-effective compared with other preventive interventions and may be cost saving. Their safety has been demonstrated in numerous studies. Health care providers should promote influenza and pneumococcal vaccination. Strategies that have been shown to be successful in increasing the use of these vaccines include provider education and feedback, flagging charts of vaccination candidates, mailed reminders to patients without fall appointments, standing orders for nurses to administer the vaccines, walk-in vaccination clinics, and vaccination of hospitalized patients at discharge.
流感和肺炎球菌感染是导致老年人或慢性病患者住院和死亡的重要原因。流感疫苗和肺炎球菌疫苗可以预防这些感染及其并发症,但大多数高危患者尚未接种。对疫苗有效性的怀疑、对副作用的恐惧以及缺乏推广疫苗使用的项目导致了这些疫苗的使用不足。尽管缺乏针对高危患者的充分对照试验,但有观察证据表明这些疫苗具有中等效力,可将流感和肺炎球菌感染的严重并发症减少约一半。与其他预防干预措施相比,它们具有成本效益,甚至可能节省成本。大量研究已证明其安全性。医疗保健提供者应推广流感和肺炎球菌疫苗接种。已被证明能成功增加这些疫苗使用的策略包括对提供者进行教育和反馈、标记疫苗接种候选人的病历、向未预约的患者邮寄提醒、为护士下达接种疫苗的常规医嘱、开设即到即种疫苗诊所,以及在患者出院时为住院患者接种疫苗。