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脊髓灰质炎疫苗。成功与争议。

Poliomyelitis vaccines. Success and controversy.

作者信息

LaForce F M

机构信息

University of Rochester School of Medicine, New York.

出版信息

Infect Dis Clin North Am. 1990 Mar;4(1):75-83.

PMID:2407779
Abstract

The conquest of poliomyelitis by killed and live poliomyelitis vaccines is arguably the most successful American public health project. In 1950, 20,000 cases of paralytic poliomyelitis were reported in the United States, whereas in recent years, fewer than 10 cases were reported. These few cases were largely associated with oral vaccine and despite their small number have led to a reconsideration of killed vaccine as a public health measure in the United States.

摘要

灭活脊髓灰质炎疫苗和减毒活脊髓灰质炎疫苗对脊髓灰质炎的征服可以说是美国最成功的公共卫生项目。1950年,美国报告了20000例麻痹性脊髓灰质炎病例,而近年来,报告的病例不到10例。这些少数病例主要与口服疫苗有关,尽管数量很少,但已促使人们重新考虑将灭活疫苗作为美国的一项公共卫生措施。

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