一种高效且经济高效的二乙酰-D-鼠李糖醛的制备方法。
An efficient and cost-effective preparation of di--acetyl-D-rhamnal.
作者信息
Miller Justin N, Pongdee Rongson
机构信息
Department of Chemistry, Sewanee: The University of the South, 735 University Avenue, Sewanee, TN 37383-1000, USA.
出版信息
Tetrahedron Lett. 2013 Jun 12;54(24):3185-3187. doi: 10.1016/j.tetlet.2013.04.035.
Abstract
We have developed a synthetic route to the frequently utilized deoxysugar building block di--acetyl-D-rhamnal originating from the inexpensive starting material methyl α-D-glucopyranoside. Our approach proceeds in five steps with minimal column chromatography purification needed to afford the title compound in good overall yield. 2009 Elsevier Ltd. All rights reserved.
摘要
我们已经开发出了一条合成路线，以廉价的起始原料α-D-吡喃葡萄糖苷为原料，合成常用的脱氧糖结构单元二乙酰基-D-鼠李糖醛。我们的方法分五步进行，只需最少的柱色谱纯化，就能以良好的总收率得到目标化合物。2009爱思唯尔有限公司。保留所有权利。
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