Department of Applied Chemistry, Faculty of Science and Technology, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama 223-8522, Japan.
Chem Commun (Camb). 2013 Nov 14;49(88):10403-5. doi: 10.1039/c3cc45275a.
Design and synthesis of a boronic acid based artificial receptor which selectively and effectively bound to a neurotransmitter, l-DOPA (), in aqueous media. In addition, the synthetic receptor was found to effectively inhibit the DDC (l-DOPA decarboxylase) enzymatic reaction under physiological conditions.
设计并合成了一种硼酸基人工受体，该受体在水相介质中对神经递质 l-DOPA()具有选择性和高效的结合能力。此外，该合成受体在生理条件下能有效地抑制 DDC(l-DOPA 脱羧酶)的酶反应。
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