Broberg Bo, Lindhardt Morten, Rossing Peter, Ibsen Hans, Persson Frederik, Rasmussen Knud
Medicinsk Afdeling, Holbæk Sygehus.
Ugeskr Laeger. 2013 Sep 30;175(40):2333-6.
Estimating glomerular filtration rate by the Modification of Diet in Renal Disease or Chronic Kidney Disease Epidemiology Collaboration formulas gives a reasonable estimate of kidney function for e.g. classification of chronic kidney disease. Additionally the estimated glomerular filtration rate is a significant predictor for cardiovascular disease and may along with classical cardiovascular risk factors add useful information to risk estimation. Several cautions need to be taken into account, e.g. rapid changes in kidney function, dialysis, high age, obesity, underweight and diverging and unanticipated deviations in muscle mass may make the estimate unreliable.
采用肾脏病饮食改良（MDRD）公式或慢性肾脏病流行病学合作（CKD-EPI）公式估算肾小球滤过率，可为慢性肾脏病的分级等提供合理的肾功能评估。此外，估算的肾小球滤过率是心血管疾病的重要预测指标，与经典心血管危险因素一起，可为风险评估增添有用信息。需要考虑一些注意事项，例如肾功能的快速变化、透析、高龄、肥胖、体重过轻以及肌肉量的差异和意外偏差可能会使估算结果不可靠。
