Transplantation Unit, Athens University School of Medicine, 'Laikon' General Hospital , Athens , Greece.
Ups J Med Sci. 2014 Mar;119(1):50-4. doi: 10.3109/03009734.2013.842618. Epub 2013 Sep 30.
Neurological complications are quite frequent in patients after solid organ transplantation presenting with focal or generalized neurologic symptoms as well as altered mental status. Posterior reversible encephalopathy syndrome is a rare cliniconeuroradiological entity characterized by headache, altered mental status, cortical blindness, seizures, and other focal neurological signs and a diagnostic magnetic resonance imaging.
We present a case of a 57-year-old woman with one episode of seizures and sudden onset of altered mental status (time and person perception) accompanied with headache at the thirtieth postoperative day after renal transplantation.
Posterior reversible encephalopathy syndrome, although an uncommon post-renal transplantation complication, should be considered in these patients, as several factors surrounding the setting of transplantation have been implicated in its development. Thus, physicians should be aware of this condition in order to establish the diagnosis and offer appropriate treatment.
在出现局灶性或全身性神经症状以及精神状态改变的实体器官移植后患者中,神经并发症相当常见。后部可逆性脑病综合征是一种罕见的临床神经影像学实体,其特征为头痛、精神状态改变、皮质盲、癫痫发作和其他局灶性神经体征以及诊断性磁共振成像。
我们报告了一例 57 岁女性患者的病例,她在肾移植后第 30 天出现一次癫痫发作和精神状态突然改变(时间和人物感知),伴有头痛。
尽管后部可逆性脑病综合征是肾移植后一种罕见的并发症,但应考虑到这些患者,因为移植环境周围的几个因素与该病的发生有关。因此,医生应该了解这种情况,以便做出诊断并提供适当的治疗。