Hagemann G, Ugur T, Witte O W, Fitzek C
Department of Neurology, Friedrich-Schiller-University, Jena, Germany.
J Hum Hypertens. 2004 Apr;18(4):287-9. doi: 10.1038/sj.jhh.1001664.
Posterior reversible encephalopathy syndrome is a proposed cliniconeuroradiological entity characterized by headache, altered mental status, cortical blindness, seizures, and other focal neurological signs, and a diagnostic magnetic resonance imaging picture. A variety of different etiologies have been reported like hypertension, pre-eclampsia/eclampsia, cyclosporin A or tacrolimus neurotoxicity, uraemia and porphyria. With early diagnosis and prompt treatment, the syndrome is usually fully reversible. We report a case of recurrent PRES of unknown aetiology following intensive care unit treatment and only moderately elevated blood pressure. Clinicians as well as radiologists must be familiar with this clinically frightening, underdiagnosed condition to assure timely diagnosis and treatment to prevent persistent deficits.
后部可逆性脑病综合征是一种拟诊的临床神经放射学疾病，其特征为头痛、精神状态改变、皮质盲、癫痫发作及其他局灶性神经体征，以及具有诊断意义的磁共振成像表现。已报道多种不同病因，如高血压、先兆子痫/子痫、环孢素A或他克莫司神经毒性、尿毒症和卟啉病。通过早期诊断和及时治疗，该综合征通常可完全逆转。我们报告1例病因不明的复发性后部可逆性脑病综合征病例，该患者在重症监护病房治疗后仅血压轻度升高。临床医生和放射科医生必须熟悉这种临床上令人恐惧但诊断不足的疾病，以确保及时诊断和治疗，防止出现持续性功能缺损。
