口服万古霉素脱敏治疗万古霉素过敏患者的艰难梭菌感染。
Oral vancomycin desensitisation to treat Clostridium difficile infection in a vancomycin allergic patient.
机构信息
Immunology Department, Beaumont Hospital, Dublin 9, Ireland.
出版信息
World Allergy Organ J. 2013 Sep 30;6(1):16. doi: 10.1186/1939-4551-6-16.
Abstract
The prevalence of Clostridium difficile infection (CDI) is increasing worldwide. Oral vancomycin is an effective and frequently used treatment. However, patients with CDI who are allergic to intravenous vancomycin cannot receive oral vancomycin due to the risk of anaphylaxis if given the oral form.We present a case where oral vancomycin desensitisation was used to successfully treat a vancomycin allergic patient with recurrent CDI.
摘要
艰难梭菌感染（CDI）的患病率在全球范围内呈上升趋势。口服万古霉素是一种有效且常用的治疗方法。然而，对静脉用万古霉素过敏的 CDI 患者由于口服剂型可能引发过敏反应的风险，不能使用口服万古霉素。我们报告了一例口服万古霉素脱敏成功治疗复发性 CDI 且对万古霉素过敏的患者。
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