H.E.J. Research Institute of Chemistry, International Centre for Chemical and Biological Sciences (ICCBS), University of Karachi, Karachi, Pakistan; NAWI Graz, Central Polymer Laboratories (CePoL), Heinrichstrasse 28 and Stremayrgasse 16, A-8010 Graz, Austria; Institute of Chemistry, Karl-Franzens-University, Heinrichstrasse 28, A-8010 Graz, Austria.
J Chromatogr A. 2013 Nov 1;1314:180-7. doi: 10.1016/j.chroma.2013.09.023. Epub 2013 Sep 11.
Telechelic oligomers based on diethylene glycol or lower polyethylene glycols and caprolactone or butene oxide can be separated according to their architecture by means of liquid chromatography under adsorption conditions for the hydrophobic block and critical or exclusion conditions for PEG. This behavior, which is predicted by the theory, can be verified by the experiment for block copolymers of ethylene oxide with ɛ-caprolactone and butene oxide. The individual peaks were identified by matrix-assisted time-of-flight mass spectrometry (MALDI-TOF-MS) of fractions obtained by semipreparative liquid chromatography at critical conditions of center block (PEG) and adsorption conditions for outer blocks (PCL and PBO).
基于二甘醇或更低分子量的聚乙二醇以及己内酯或丁烯氧化物的端基齐聚物可以根据其结构通过吸附条件下的液相色谱法进行分离，对于疏水性嵌段采用吸附条件，对于聚乙二醇采用临界或排除条件。这种行为可以通过实验验证，实验对象为氧化乙烯与ε-己内酯和氧化丁烯的嵌段共聚物。通过在中心嵌段（PEG）的临界条件和外嵌段（PCL 和 PBO）的吸附条件下通过半制备液相色谱法获得的级分的基质辅助飞行时间质谱法（MALDI-TOF-MS）对各个峰进行了鉴定。
