Department of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, 81 Mei Shan Road, Hefei 230032, Anhui, China; Anhui Provincial Key Laboratory of Population Health & Aristogenics, Hefei 230032, Anhui, China; Department of Child and Adolescent Health, School of Public Health, Nantong University, Nantong, Jiangsu, China.
Appetite. 2014 Jan;72:13-20. doi: 10.1016/j.appet.2013.09.019. Epub 2013 Sep 27.
The purpose of this study is to test the relation of cortisol reactivity, delay discounting and percent body fat (PBF) in adolescents aged 12-13 years (N=87), and evaluate the delay discounting as potential components in models of adolescent obesity. Anthropometry and body composition measurements were assessed in adolescents. The cortisol reactivity to Trier Social Stress Test for Children (TSST-C) and delay discounting were measured. The result showed increased cortisol reactivity and greater delay discounting were associated with higher PBF in girls. Structural equation modeling supported greater delay discounting as a mediator of relations between increased cortisol reactivity and PBF in adolescent girls. The proposed mediation model indicated that cortisol reactivity is linked to PBF through delay discounting, thereby supporting a significant indirect relationship. The direct relationship between increased cortisol reactivity and higher PBF was significant in a model that did not include delay discounting, and was still significant in the mediation model that included delay discounting. This study provides the first evidence that greater delay discounting may partially account for the relationship of hyperactivity of the HPA-axis and higher PBF in girls.
本研究旨在测试 12-13 岁青少年的皮质醇反应性、延迟折扣与体脂百分比（PBF）之间的关系，并评估延迟折扣是否为青少年肥胖模型中的潜在因素。对青少年进行了人体测量和身体成分测量。测量了皮质醇对特里尔社会压力测试儿童版（TSST-C）的反应和延迟折扣。结果表明，皮质醇反应性增加和更大的延迟折扣与女孩的 PBF 更高有关。结构方程模型支持更大的延迟折扣作为皮质醇反应性和青少年女孩 PBF 之间关系的中介。提出的中介模型表明，皮质醇反应性通过延迟折扣与 PBF 相关，从而支持了显著的间接关系。在不包括延迟折扣的模型中，皮质醇反应性增加与更高的 PBF 之间存在显著的直接关系，而在包括延迟折扣的中介模型中，这种关系仍然显著。本研究首次提供证据表明，更大的延迟折扣可能部分解释了 HPA 轴活性增加与女孩 PBF 更高之间的关系。
