Chandraker Anil, Strom Terry B
Transplantation Research Center, Renal Division, Brigham & Women's Hospital, Harvard Medical School, 221 Longwood Avenue, Boston, MA 02215, USA.
Nat Rev Nephrol. 2013 Nov;9(11):631-2. doi: 10.1038/nrneph.2013.199. Epub 2013 Oct 1.
Renal biopsy is the gold standard for detection of rejection in kidney transplant recipients, but is not considered until evidence of renal dysfunction is apparent. Now, Suthanthiran and colleagues suggest that mRNA levels in urinary cells from these patients might be diagnostic and prognostic of acute cellular rejection.
肾活检是检测肾移植受者排斥反应的金标准，但在肾功能障碍证据明显之前不会考虑进行。现在，苏坦西兰及其同事表明，这些患者尿液细胞中的mRNA水平可能对急性细胞排斥反应具有诊断和预后价值。
