Croisile B, Piperno D, Bascoulergue Y, Romestaing P, Trillet M, Aimard G, Perrin-Fayolle M
Service de Neurologie, Hôpital Neurologique, Lyon.
Rev Neurol (Paris). 1990;146(1):57-60.
A 47 year-old man developed rapid visual loss, visual field defects and memory disturbances after radiotherapy with conventional doses for a pituitary metastasis from a renal carcinoma. CT and MRI did not show recurrent tumour, pituitary apoplexy or empty sella. Eventually, T2-weighted MRI images showed abnormal high signals in the optic chiasm, the left mesial temporal lobe and the right inferior frontal lobe, supporting the diagnosis of delayed radionecrosis. The role of chemotherapy associated with radiotherapy is discussed.
一名47岁男性在接受常规剂量放疗治疗肾癌垂体转移瘤后,出现了快速视力丧失、视野缺损和记忆障碍。CT和MRI未显示肿瘤复发、垂体卒中或空蝶鞍。最终,T2加权MRI图像显示视交叉、左侧颞叶内侧和右侧额叶下部有异常高信号,支持延迟放射性坏死的诊断。本文讨论了化疗联合放疗的作用。