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预防与酒精相关的出生缺陷:综述

Preventing alcohol related birth damage: a review.

作者信息

Waterson E J, Murray-Lyon I M

机构信息

Gastrointestinal Unit, Charing Cross Hospital, London, England.

出版信息

Soc Sci Med. 1990;30(3):349-64. doi: 10.1016/0277-9536(90)90190-4.

DOI:10.1016/0277-9536(90)90190-4
PMID:2408151
Abstract

Since 1974 numerous clinical studies have made it clear that heavy alcohol consumption during pregnancy (in excess of 80 g or 8 units daily) can result in a child being born with a specific combination of physical and mental disabilities known as the Fetal Alcohol Syndrome. More moderate levels of intake (as little as 10 g of 1 unit daily) are associated with other fetal problems known as Fetal Alcohol Effects. The most common of these is growth retardation. Reduction of alcohol consumption is beneficial to pregnancy outcome. However, despite this great clinical and research interest within the field there has been comparatively little attention paid to researching possible preventative strategies and appropriate policy development. This paper first describes the size of the problem posed by drinking in pregnancy in the U.S.A. and the U.K., detailing the contrasting policy response on either side of the Atlantic. It examines the difficulties of formulating appropriate advice and then assesses the available research reports on preventative measures. The strategies described include general publicity and counselling for pregnant women. In addition, attention has been paid to the problems of dissemination by emphasising professional education. One major shortcoming is that most of these studies appear to have been carried out with little reference to existing knowledge on health education and promotion, or educational work in the antenatal or alcohol fields. In addition, little attention appears to have been paid to the characteristics of the groups at whom intervention might be targeted or the underlying social or psychological factors which maintain drinking in these groups. The second part of this paper, therefore, attempts to suggest appropriate avenues for developing preventative strategies by presenting a wide-ranging review with special reference to British experience. Particular attention is given to the issues of form and content of appropriate messages, targeting of risk populations, the venue for intervention, and media and the actual mechanisms involved in implementing the programme. We conclude that women should be advised to limit their alcohol consumption to no more than one unit a day when they are either pregnant or planning a pregnancy. We recommend that pregnant women should be asked about their alcohol and given appropriate advice during routine antenatal clinic visits. We suggest that the form of advice should be designed with the characteristics of the risk population in mind.(ABSTRACT TRUNCATED AT 400 WORDS)

摘要

自1974年以来,大量临床研究已明确表明,孕期大量饮酒(每天超过80克或8个单位)会导致孩子出生时患有一系列特定的身心残疾,即胎儿酒精综合征。饮酒量处于中度水平(低至每天10克或1个单位)则与其他胎儿问题相关,即胎儿酒精影响。其中最常见的是生长发育迟缓。减少饮酒量对妊娠结局有益。然而,尽管该领域在临床和研究方面备受关注,但对研究可能的预防策略及制定适当政策的关注相对较少。本文首先描述了美国和英国孕期饮酒所带来问题的规模,详细阐述了大西洋两岸截然不同的政策应对措施。文章探讨了制定适当建议的困难,然后评估了关于预防措施的现有研究报告。所描述的策略包括针对孕妇的广泛宣传和咨询。此外,通过强调专业教育来关注传播问题。一个主要缺点是,这些研究大多在开展时几乎未参考健康教育与促进方面的现有知识,也未参考产前或酒精领域的教育工作。此外,似乎很少关注干预可能针对的群体的特征,或维持这些群体饮酒行为的潜在社会或心理因素。因此,本文第二部分试图通过进行广泛综述并特别参考英国经验,为制定预防策略提出适当途径。特别关注适当信息的形式和内容、风险人群的定位、干预场所、媒体以及实施该计划所涉及的实际机制等问题。我们得出结论,应建议女性在怀孕或计划怀孕时,将饮酒量限制在每天不超过一个单位。我们建议在常规产前门诊就诊时询问孕妇的饮酒情况并给予适当建议。我们建议在设计建议形式时应考虑风险人群的特征。(摘要截选至400字)

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Alcohol Health Res World. 1994;18(1):86-92.
2
Psychological and/or educational interventions for reducing alcohol consumption in pregnant women and women planning pregnancy.减少孕妇及备孕女性饮酒量的心理和/或教育干预措施。
Cochrane Database Syst Rev. 2009 Apr 15(2):CD004228. doi: 10.1002/14651858.CD004228.pub2.
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Motivational interventions in prenatal clinics.产前诊所的动机干预措施。
Alcohol Res Health. 2001;25(3):219-21-9.
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Br J Gen Pract. 1998 Feb;48(427):963-6.
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Youth beliefs and knowledge about the risks of drinking while pregnant.青少年关于孕期饮酒风险的信念和知识。
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