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边界软骨润滑:当前概念综述

Boundary cartilage lubrication: review of current concepts.

作者信息

Daniel Matej

机构信息

Division of biomechanics, Department of mechanics, biomechanics and mechatronics, Faculty of Mechanical Engineering, Czech Technical University in Prague, Technicka 4, 16607, Prague 6, Czech Republic,

出版信息

Wien Med Wochenschr. 2014 Mar;164(5-6):88-94. doi: 10.1007/s10354-013-0240-2. Epub 2013 Oct 1.

Abstract

Effective lubrication of synovial joints is important to prevent cartilage degeneration and to keep the joints healthy. This paper sets out the basics of engineering lubrication with respect to the composition and properties of synovial fluid constituents. Two basic types of boundary lubrication are discussed: the presence of highly hydrophilic proteoglycans that provide a water liquid film, and the existence of multilamellar phospholipids lubricating layers at the surface ofarticular cartilage. Based on current knowledge, we may conclude that no single mechanism of boundary lubrication exists, and that effective boundary lubrication of synovial joints is maintained by the synergic effect of all synovial fluid constituents.

摘要

滑膜关节的有效润滑对于防止软骨退变和保持关节健康至关重要。本文阐述了与滑液成分的组成和特性相关的工程润滑基础知识。讨论了两种基本类型的边界润滑:存在提供水液膜的高度亲水性蛋白聚糖,以及在关节软骨表面存在多层磷脂润滑层。基于目前的知识,我们可以得出结论,不存在单一的边界润滑机制,滑膜关节的有效边界润滑是由所有滑液成分的协同作用维持的。

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