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儿童期精神药物使用的全国趋势:1994-2009 年。

National trends in psychotropic medication use in young children: 1994-2009.

机构信息

Cincinnati Children's Hospital Medical Center, 3333 Burnet Ave, Mail Location 4002, Cincinnati, OH 45229.

出版信息

Pediatrics. 2013 Oct;132(4):615-23. doi: 10.1542/peds.2013-1546. Epub 2013 Sep 30.

Abstract

OBJECTIVE

To examine recent national trends in psychotropic use for very young children at US outpatient medical visits.

METHODS

Data for 2- to 5-year-old children (N = 43 598) from the 1994-2009 National Ambulatory and National Hospital Ambulatory Medical Care Surveys were used to estimate the weighted percentage of visits with psychotropic prescriptions. Multivariable logistic regression was used to identify factors associated with psychotropic use. Time effects were examined in 4-year blocks (1994-1997, 1998-2001, 2002-2005, and 2006-2009).

RESULTS

Psychotropic prescription rates were 0.98% from 1994-1997, 0.83% from 1998-2001, 1.45% from 2002-2005, and 1.00% from 2006-2009. The likelihood of preschool psychotropic use was highest in 2002-2005 (1994-1997 adjusted odds ratio [AOR] versus 2002-2005: 0.67; 1998-2001 AOR versus 2002-2005: 0.63; 2006-2009 AOR versus 2002-2005: 0.64), then diminished such that the 2006-2009 probability of use did not differ from 1994-1997 or from 1998-2001. Boys (AOR versus girls: 1.64), white children (AOR versus other race: 1.42), older children (AOR for 4 to 5 vs 2 to 3 year olds: 3.87), and those lacking private insurance (AOR versus privately insured: 2.38) were more likely than children from other groups to receive psychotropic prescriptions.

CONCLUSIONS

Psychotropic prescription was notable for peak usage in 2002-2005 and sociodemographic disparities in use. Further study is needed to discern why psychotropic use in very young children stabilized in 2006-2009, as well as reasons for increased use in boys, white children, and those lacking private health insurance.

摘要

目的

研究美国门诊就诊的 2-5 岁儿童中精神药物使用的近期全国趋势。

方法

利用 1994-2009 年全国门诊和全国医院门诊医疗调查中 2-5 岁儿童(N=43598)的数据,估计有精神药物处方的就诊比例。采用多变量逻辑回归来确定与精神药物使用相关的因素。在 4 年块(1994-1997 年、1998-2001 年、2002-2005 年和 2006-2009 年)中检查时间效应。

结果

1994-1997 年精神药物处方率为 0.98%,1998-2001 年为 0.83%,2002-2005 年为 1.45%,2006-2009 年为 1.00%。2002-2005 年幼儿使用精神药物的可能性最高(1994-1997 年调整后的优势比[OR]与 2002-2005 年相比:0.67;1998-2001 年 OR 与 2002-2005 年相比:0.63;2006-2009 年 OR 与 2002-2005 年相比:0.64),然后减少,以至于 2006-2009 年的使用概率与 1994-1997 年或 1998-2001 年没有差异。男孩(OR 与女孩相比:1.64)、白人儿童(OR 与其他种族相比:1.42)、年龄较大的儿童(4 至 5 岁与 2 至 3 岁相比的 OR:3.87)和没有私人保险的儿童(OR 与私人保险相比:2.38)比其他群体的儿童更有可能接受精神药物处方。

结论

精神药物的使用在 2002-2005 年达到高峰,并且在使用方面存在社会人口统计学差异。需要进一步研究以了解为什么幼儿的精神药物使用在 2006-2009 年稳定下来,以及男孩、白人儿童和没有私人医疗保险的儿童使用增加的原因。

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