Sacchi S, Curci G, Piccinini L, Cucci F, Messerotti A, Roncaia R, Benedetti P G
Scand J Clin Lab Invest. 1985 Apr;45(2):165-8. doi: 10.3109/00365518509160990.
We studied beta-thromboglobulin (BTG) and platelet factor 4 (PF4) plasma levels in 90 diabetic subjects; we found high plasma values of these proteins only in patients with complications. To provide further indications regarding the role of platelet activation in the pathogenesis of diabetic microangiopathy, we also tested mobilizable platelet content of BTG and PF4; we found these similar to those of normal subjects.
我们研究了90名糖尿病患者的β-血小板球蛋白(BTG)和血小板因子4(PF4)血浆水平;我们发现只有出现并发症的患者这些蛋白质的血浆值才高。为了进一步说明血小板活化在糖尿病微血管病变发病机制中的作用,我们还检测了BTG和PF4的可动员血小板含量;我们发现这些含量与正常受试者的相似。