腹腔镜肝切除术作为结直肠癌肝转移开放切除术的一种安全有效的替代方法：一项荟萃分析。
Laparoscopic liver resection as a safe and efficacious alternative to open resection for colorectal liver metastasis: a meta-analysis.
作者信息
Zhou Yanming, Xiao Yaqing, Wu Lupeng, Li Bin, Li Hua
机构信息
Department of Hepatobiliary & Pancreatovascular Surgery, Oncologic Center of Xiamen, First affiliated Hospital of Xiamen University, Xiamen, China.
出版信息
BMC Surg. 2013 Oct 1;13:44. doi: 10.1186/1471-2482-13-44.
BACKGROUND
The safety and efficacy of laparoscopic liver resection (LLR) for colorectal liver metastasis (CLM) remain to be established. A meta-analysis was undertaken to compare LLR and open liver resection (OLR) for CLM with respect to surgical and oncologic outcomes.
METHODS
An electronic search was performed to retrieve all relevant articles published in the English language by the end of March 2013. Data were analyzed using Review Manager version 5.0.
RESULTS
A total of 8 nonrandomized controlled studies with 695 subjects were analyzsed. Intra-operative blood loss, the proportion of patients requiring blood transfusion, morbidity and the length of hospital stay were all significantly reduced after LLR. Postoperative recurrence, 5-year overall and disease-free survivals were comparable between two groups.
CONCLUSIONS
LLR for CLM is safe and efficacious. It improves surgical outcomes and uncompromises oncologic outcomes as compared with OLR.
背景
腹腔镜肝切除术（LLR）治疗结直肠癌肝转移（CLM）的安全性和有效性仍有待确定。进行了一项荟萃分析，以比较LLR和开腹肝切除术（OLR）治疗CLM的手术和肿瘤学结局。
方法
进行电子检索，以检索截至2013年3月底以英文发表的所有相关文章。使用Review Manager 5.0版分析数据。
结果
共分析了8项非随机对照研究，涉及695名受试者。LLR术后术中失血量、需要输血的患者比例、发病率和住院时间均显著降低。两组术后复发率、5年总生存率和无病生存率相当。
结论
LLR治疗CLM是安全有效的。与OLR相比，它改善了手术结局且不影响肿瘤学结局。
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