Heaney Jennifer L J, Carroll Douglas, Phillips Anna C
School of Sport and Exercise Sciences, University of Birmingham, Birmingham, West Midlands, England, UK.
J Aging Phys Act. 2014 Oct;22(4):465-73. doi: 10.1123/japa.2012-0082. Epub 2013 Oct 1.
The present study examined the relationship between habitual physical activity, life events stress, the diurnal rhythms of cortisol and DHEA, and the cortisol:dehydroepiandrosterone (DHEA) ratio in older adults. Thirty-six participants aged ≥ 65 reported their habitual physical activity, and indicated if a particular event happened to them in the past year (stress incidence) and how stressful they perceived the event to be (stress severity). Older adults with higher stress severity demonstrated a significantly higher cortisol:DHEA ratio. Individuals with higher stress incidence scores and who did not participate in aerobic exercise had a significantly higher cortisol:DHEA ratio and flatter DHEA diurnal rhythm compared with those who regularly participated in aerobic exercise. In conclusion, life events stress may have a negative impact on the cortisol:DHEA ratio in older adults. Under conditions of high stress exposure, exercise may protect older adults from an increased cortisol:DHEA ratio and flatter DHEA diurnal rhythm.
本研究调查了老年人习惯性身体活动、生活事件压力、皮质醇和脱氢表雄酮的昼夜节律以及皮质醇与脱氢表雄酮（DHEA）比值之间的关系。36名年龄≥65岁的参与者报告了他们的习惯性身体活动，并指出过去一年中是否发生过特定事件（压力发生率）以及他们认为该事件的压力程度如何（压力严重程度）。压力严重程度较高的老年人表现出显著更高的皮质醇与脱氢表雄酮比值。与经常参加有氧运动的人相比，压力发生率得分较高且不参加有氧运动的人的皮质醇与脱氢表雄酮比值显著更高，脱氢表雄酮昼夜节律更平缓。总之，生活事件压力可能会对老年人的皮质醇与脱氢表雄酮比值产生负面影响。在高压力暴露条件下，运动可能会保护老年人避免皮质醇与脱氢表雄酮比值升高以及脱氢表雄酮昼夜节律变平缓。
