Sentis H J, Willemze R, Van Vloten W A
Acta Derm Venereol. 1985;65(2):179-83.
Seventeen patients with mycosis fungoides and lymph node involvement were treated with polycytostatic courses consisting of cyclophosphamide, vincristin (Oncovin) and prednisone (COP). A response rate of 76% was found. In 7 patients (41%) a complete remission and in 6 patients (35%) a partial remission was obtained. The actuarial survival rate at 5 years was 64%. This treatment was well-tolerated by most patients and severe side effects were not observed.
17例蕈样肉芽肿伴淋巴结受累患者接受了由环磷酰胺、长春新碱(安可平)和泼尼松(COP)组成的多细胞毒性疗程治疗。发现缓解率为76%。7例患者(41%)获得完全缓解,6例患者(35%)获得部分缓解。5年精算生存率为64%。大多数患者对这种治疗耐受性良好,未观察到严重副作用。