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蕈样肉芽肿伴淋巴结受累患者的全身多药化疗:17例患者的随访研究

Systemic polychemotherapy in patients with mycosis fungoides and lymph node involvement: a follow-up study of 17 patients.

作者信息

Sentis H J, Willemze R, Van Vloten W A

出版信息

Acta Derm Venereol. 1985;65(2):179-83.

PMID:2408428
Abstract

Seventeen patients with mycosis fungoides and lymph node involvement were treated with polycytostatic courses consisting of cyclophosphamide, vincristin (Oncovin) and prednisone (COP). A response rate of 76% was found. In 7 patients (41%) a complete remission and in 6 patients (35%) a partial remission was obtained. The actuarial survival rate at 5 years was 64%. This treatment was well-tolerated by most patients and severe side effects were not observed.

摘要

17例蕈样肉芽肿伴淋巴结受累患者接受了由环磷酰胺、长春新碱(安可平)和泼尼松(COP)组成的多细胞毒性疗程治疗。发现缓解率为76%。7例患者(41%)获得完全缓解,6例患者(35%)获得部分缓解。5年精算生存率为64%。大多数患者对这种治疗耐受性良好,未观察到严重副作用。

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