Molin L, Thomsen K, Volden G, Groth O, Hellbe L, Holst R, Knudsen E A, Roupe G, Schmidt H
Acta Derm Venereol. 1980;60(6):542-4.
Combination chemotherapy with cyclophosphamide, vincristine, VP-16, adriamycin and prednisolone was given in 9 cases of mycosis fungoides in the tumor stage; 3 of these patients received COP, one received CHOP, and 5 CAVOP. Complete remission was obtained in one case and partial remission in 5, the response rate thus being 6/9. It was impossible, however, to maintain remission. The treatment was reduced or withdrawn owing to toxic effects in 4 cases. These forms of combination chemotherapy are beneficial in non-Hodgkin lymphomas but do not seem to be of value in the tumour stage of mycosis fungoides.
对9例肿瘤期蕈样肉芽肿患者给予环磷酰胺、长春新碱、依托泊苷、阿霉素和泼尼松龙联合化疗；其中3例患者接受COP方案，1例接受CHOP方案，5例接受CAVOP方案。1例患者获得完全缓解，5例部分缓解，缓解率为6/9。然而，缓解无法维持。4例患者因毒性作用而减少或停止治疗。这些联合化疗方案对非霍奇金淋巴瘤有益，但对蕈样肉芽肿肿瘤期似乎没有价值。
