Obstet Gynecol. 2013 Oct;122(4):918-930. doi: 10.1097/01.AOG.0000435415.21944.8f.
Preterm delivery occurs in approximately 12% of all births in the United States and is a major factor that contributes to perinatal morbidity and mortality (). Preterm premature rupture of membranes (PROM) complicates approximately 3% of all pregnancies in the United States (). The optimal approach to clinical assessment and treatment of women with term and preterm PROM remains controversial. Management hinges on knowledge of gestational age and evaluation of the relative risks of delivery versus the risks of expectant management (eg, infection, abruptio placentae, and umbilical cord accident). The purpose of this document is to review the current understanding of this condition and to provide management guidelines that have been validated by appropriately conducted outcome-based research when available. Additional guidelines on the basis of consensus and expert opinion also are presented.
在美国，大约 12%的分娩为早产，这是围产期发病率和死亡率的主要因素。在美国，大约 3%的所有妊娠都并发胎膜早破（）。对于足月和早产胎膜早破的妇女，临床评估和治疗的最佳方法仍存在争议。管理取决于对胎龄的了解以及对分娩风险与期待管理风险（例如感染、胎盘早剥和脐带意外）的相对风险的评估。本文旨在回顾对这种情况的现有认识，并在可行的情况下提供经过适当的基于结果的研究验证的管理指南。此外，还根据共识和专家意见提出了其他指南。
