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线虫秀丽隐杆线虫中的多巴胺能神经元。

Dopaminergic neurons in the nematode Caenorhabditis elegans.

作者信息

Sulston J, Dew M, Brenner S

出版信息

J Comp Neurol. 1975 Sep 15;163(2):215-26. doi: 10.1002/cne.901630207.

Abstract

Dopamine is the putative transmitter of eight neurons in the hermaphrodite form of the nematode Caenorhabditis elegans. These include the cephalic and deirid neurons, which are believed to be mechanosensory. The male has an additional six dopaminergic neurons in the tail. Mutants have been selected which have defects in the formaldehyde induced fluorescence and lack dopamine to varying degrees, but they are not insensitive to touch. The dopaminergic neurons of C. elegans are compared with the homologous neurons in Ascaris lumbricoides.

摘要

多巴胺是线虫秀丽隐杆线虫雌雄同体形式中八个神经元的假定递质。这些神经元包括头部和化感器神经元,它们被认为是机械感觉神经元。雄性线虫在尾部还有另外六个多巴胺能神经元。已经筛选出了一些突变体,这些突变体在甲醛诱导荧光方面存在缺陷,并且在不同程度上缺乏多巴胺,但它们对触摸并不不敏感。将秀丽隐杆线虫的多巴胺能神经元与蛔虫中的同源神经元进行了比较。

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