a Department of Pharmacy, Health and Nutritional Sciences , University of Calabria , I-87036 Rende (CS) , Italy.
Nat Prod Res. 2014;28(4):271-4. doi: 10.1080/14786419.2013.841689. Epub 2013 Oct 2.
Leaves, bark and woody part of Ficus carica L. cultivar Dottato collected in different months were examined to assess their chemical composition, antioxidant activity and phototoxicity on C32 human melanoma cells after UVA irradiation. The phytochemical investigation revealed different composition in the coumarin, fatty acid, polyphenol and flavonoid content. The second harvest of leaves and the first harvest of the bark possessed the highest antiradical activity with IC50 values of 64.00 ± 0.59 and 67.00 ± 1.09 μg/mL, respectively. Harvest III of leaves showed the best inhibition of lipid peroxidation (IC50 = 1.48 ± 0.04 μg/mL). Leaf samples of F. carica showed also the best antiproliferative activity in comparison with bark and woody part of F. carica.
不同月份采集的 Dottato 品种普通榕树叶、树皮和木质部分进行了化学组成、抗氧化活性和 UVA 照射后对 C32 人黑色素瘤细胞光毒性的评估。植物化学研究表明，香豆素、脂肪酸、多酚和类黄酮含量存在不同的组成。第二茬叶和第一茬树皮具有最高的自由基清除活性，IC50 值分别为 64.00±0.59 和 67.00±1.09μg/mL。第三茬叶表现出最好的抑制脂质过氧化作用（IC50=1.48±0.04μg/mL）。与普通榕树皮和木质部分相比，普通榕树叶的样品显示出最好的抗增殖活性。
