Rynans Sylwia, Dzieciątkowski Tomasz, Młynarczyk Grażyna
Katedra i Zakład Mikrobiologii Lekarskiej, Warszawski Uniwersytet Medyczny.
Postepy Hig Med Dosw (Online). 2013 Sep 11;67:964-72. doi: 10.5604/17322693.1066199.
Human adenoviruses belong to the Adenoviridae family and they are divided into seven species, including 56 types. Adenoviruses are common opportunistic pathogens that are rarely associated with clinical symptoms in immunocompetent patients. However, they are emerging pathogens causing morbidity and mortality in recipients of hematopoietic stem cell and solid organ transplants, HIV infected patients and patients with primary immune deficiencies. Clinical presentation ranges from asymptomatic viraemia to respiratory and gastrointestinal disease, haemorrhagic cystitis and severe disseminated illness. There is currently no formally approved therapy for the treatment of adenovirus infections. This article presents current knowledge about adenoviruses, their pathogenicity and information about available methods to diagnose and treat adenoviral infections.
人腺病毒属于腺病毒科，分为7个种，包括56个型别。腺病毒是常见的机会性病原体，在免疫功能正常的患者中很少引起临床症状。然而，它们是造血干细胞和实体器官移植受者、HIV感染患者以及原发性免疫缺陷患者中导致发病和死亡的新兴病原体。临床表现从无症状病毒血症到呼吸道和胃肠道疾病、出血性膀胱炎以及严重的播散性疾病。目前尚无正式批准用于治疗腺病毒感染的疗法。本文介绍了有关腺病毒的现有知识、它们的致病性以及可用的腺病毒感染诊断和治疗方法的信息。
