Iguchi Eriko, Tsumura Takehiko, Sekikawa Akira, Wakasa Tomoko, Maruo Takanori, Okabe Yoshihiro, Kimura Toru, Osaki Yukio
Department of Gastroenterology and Hepatology, Osaka Red Cross Hospital, Japan.
Intern Med. 2013;52(19):2215-8. doi: 10.2169/internalmedicine.52.0700. Epub 2012 Mar 1.
We herein report the case of a 43-year-old man with distinct gastropathy and hypoproteinemia treated with H. pylori eradication therapy. Most reported cases of protein-losing gastropathy are divided into Ménétrier's disease (MD) and diffuse varioliform gastritis (DVG). Our patient presented with leg edema due to marked hypoalbuminemia, which we ascribed to distinct gastropathy with novel endoscopic findings resembling cap polyposis in the colon, apparently different from both MD and DVG. H. pylori eradication therapy promptly induced the normalization of laboratory data and mucosal healing. Our case together with two previously published similar cases may contribute to establishing an association between cap-polyposis-like-gastropathy with hypoproteinemia and H. pylori.
