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自发性椎动脉夹层导致的单侧颈后脊髓梗死

Unilateral posterior cervical spinal cord infarction due to spontaneous vertebral artery dissection.

作者信息

Richard Sébastien, Abdallah Chifaou, Chanson Anne, Foscolo Sylvain, Baillot Pierre-Alexandre, Ducrocq Xavier

出版信息

J Spinal Cord Med. 2014 Mar;37(2):233-6. doi: 10.1179/2045772313Y.0000000125. Epub 2013 Nov 26.

Abstract

CONTEXT

Ischemia of the cervical spinal cord is a rare complication of spontaneous vertebral artery dissection (VAD) and usually involves the ventral portion. We describe a less evocative clinical presentation and images of unilateral posterior spinal cord infarction due to spontaneous VAD in order to facilitate early diagnosis.

FINDINGS

A previously fit 30-year-old man presented with persistent headaches and proximal motor deficit of the right arm. He was diagnosed with spontaneous dissection of both vertebral arteries, with occlusion of the right one, and the right carotid artery. Neurological examination also revealed a right C2-C3 tactile sensory loss, with unilateral proprioceptive deficit below. Brain images revealed small bilateral cerebellar infarcts which could not be responsible for the clinical symptoms. Magnetic resonance imaging of the spinal cord showed a right posterior cervical spinal cord infarction. The patient achieved nearly complete recovery after several weeks of anticoagulation and rehabilitation.

CONCLUSION AND CLINICAL RELEVANCE

Infarction of the caudal portion of the cervical spinal cord, especially unilateral, caused by spontaneous VAD, has rarely been described and is certainly under-diagnosed due to less suggestive symptoms, like unilateral and mainly sensory deficit. Nevertheless, early diagnosis of this condition is important to guide patient management and rehabilitation.

摘要

背景

颈脊髓缺血是自发性椎动脉夹层(VAD)的一种罕见并发症,通常累及腹侧部分。我们描述了一例因自发性VAD导致的单侧脊髓后梗死的不太典型的临床表现及影像学表现,以促进早期诊断。

发现

一名既往健康的30岁男性出现持续性头痛及右臂近端运动功能障碍。他被诊断为双侧椎动脉自发性夹层,右侧椎动脉及右侧颈动脉闭塞。神经系统检查还发现右侧C2 - C3触觉感觉丧失,其下方存在单侧本体感觉障碍。脑部影像学检查显示双侧小脑小梗死灶,这不能解释临床症状。脊髓磁共振成像显示右侧颈段脊髓后梗死。经过数周的抗凝及康复治疗,患者几乎完全康复。

结论及临床意义

由自发性VAD引起的颈段脊髓尾端梗死,尤其是单侧梗死,鲜有报道,且由于症状缺乏特异性,如单侧且主要为感觉障碍,肯定存在诊断不足的情况。然而,早期诊断这种疾病对于指导患者管理及康复很重要。

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