Department of Radiology, Kinki University, Faculty of Medicine, Osaka-Sayama, Japan.
Department of Radiology, Kinki University, Faculty of Medicine, Osaka-Sayama, Japan.
Clin Radiol. 2014 Jan;69(1):41-4. doi: 10.1016/j.crad.2013.08.002. Epub 2013 Sep 30.
To report the magnetic resonance imaging (MRI) and corresponding histopathological features of squamous cell carcinoma (SCC) originating in the parotid gland.
The MRI images of seven patients with histopathologically proven SCC originating in the parotid gland were reviewed retrospectively, with an emphasis on tumour size, shape, contour definition, extraparotid infiltration, signal characteristics, and the presence of central necrosis. These were correlated with the microscopic findings of the surgical specimens.
The tumours ranged in size from 3.9-7 cm (mean 4.7 cm). All tumours had an ill-defined margin with extraparotid infiltration, which seemed to reflect the invasive growth of the tumour cells on histopathological examination. The solid portions of the tumours showed predominantly low to intermediate signal intensities on T2-weighted images, which seemed to reflect the high cellularity, intercellular bridges, and/or keratin pearl formation observed at histopathological examination. Five of the seven tumours had central necrosis.
A relatively large tumour with central necrosis is a useful imaging feature of SCCs originating in the parotid gland, in addition to the well-recognized indicators of parotid malignancy, such as an ill-defined margin, extraparotid infiltration, and low to intermediate signal intensity on T2-weighted images.
报告源于腮腺的鳞状细胞癌（SCC）的磁共振成像（MRI）和相应的组织病理学特征。
回顾性分析 7 例经组织病理学证实的源于腮腺 SCC 的 MRI 图像，重点分析肿瘤大小、形状、轮廓定义、腮腺外浸润、信号特征以及中央坏死的存在，并与手术标本的显微镜检查结果相关联。
肿瘤大小为 3.9-7 cm（平均 4.7 cm）。所有肿瘤均边界不清，有腮腺外浸润，这似乎反映了肿瘤细胞在组织病理学检查中的侵袭性生长。肿瘤的实性部分在 T2 加权图像上主要表现为低到中等信号强度，这似乎反映了组织病理学检查中观察到的高细胞密度、细胞间桥和/或角蛋白珠形成。7 例肿瘤中有 5 例有中央坏死。
除了腮腺恶性肿瘤的公认指标，如边界不清、腮腺外浸润和 T2 加权图像上的低到中等信号强度外，相对较大的肿瘤伴中央坏死是源于腮腺 SCC 的一种有用的影像学特征。
