*HIV, STDs, and Reproductive Health Program, Louisiana Public Health Institute, New Orleans, LA; †Department of Epidemiology and Biostatistics, The George Washington University School of Public Health and Health Services, Washington, DC; ‡Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA; §Fenway Health and Infectious Disease Division, The Fenway Institute, Boston, MA; ‖Beth Israel Deaconess Hospital, Boston, MA; and ¶Harvard Medical School, Boston, MA.
J Acquir Immune Defic Syndr. 2014 Feb 1;65(2):218-25. doi: 10.1097/01.qai.0000434953.65620.3d.
This study examined the predictors of new incarceration and their association with HIV infection among 1278 black men who have sex with men enrolled and followed up in the HIV Prevention Trials Network 061 study. HIV Prevention Trials Network 061 was conducted to determine the feasibility and acceptability of a multicomponent intervention to reduce HIV infection among BMSM in 6 US cities. In this study, multivariable logistic regression models were used to explore the association between incarceration during study follow-up and several demographic, behavioral, and psychosocial variables at baseline found to be significant in bivariate analyses. In addition, Cox proportional hazard regression was used to explore the association between incarceration during study follow-up and incident HIV infection. Among the 1278 BMSM with follow-up data, 305 (24%) reported a new incarceration within 1 year of entering the study with an estimated incarceration incidence of 35% (95% confidence interval: 31% to 38%). After adjusting for confounders, lower education, lower annual income, previous incarceration frequency, and higher levels of perceived racism were significantly associated with new incarcerations during study follow-up. There was no observed association between incarceration during study follow-up and incident HIV infection. The very high level of new incarcerations highlights the importance of structural-level interventions to prevent incarceration among economically disenfranchised black men who have sex with men in the United States.
本研究调查了 1278 名男男性行为者（MSM）新入狱的预测因素及其与 HIV 感染的关联，这些参与者参加并随访了 HIV 预防试验网络 061 研究。HIV 预防试验网络 061 旨在确定一种多组分干预措施在美国 6 个城市减少 MSM 中 HIV 感染的可行性和可接受性。在这项研究中，使用多变量逻辑回归模型探讨了随访期间入狱与基线时在双变量分析中发现的几个人口统计学、行为和心理社会变量之间的关联。此外，还使用 Cox 比例风险回归模型探讨了随访期间入狱与新发 HIV 感染之间的关联。在具有随访数据的 1278 名 MSM 中，有 305 名（24%）报告在进入研究后 1 年内新入狱，估计入狱发生率为 35%（95%置信区间：31%至 38%）。在校正混杂因素后，较低的教育程度、较低的年收入、以前入狱的频率和更高的感知种族主义水平与随访期间的新入狱显著相关。在随访期间入狱与新发 HIV 感染之间没有观察到关联。新入狱率非常高，突显了在美国经济上处于不利地位的黑人 MSM 中预防入狱需要采取结构性干预措施的重要性。
