Département de Bactériologie-Virologie, Institut Pasteur de Côte d'Ivoire, 01 BP 490 Abidjan 01, Cote D'Ivoire ; Thérapeutiques Cliniques et Expérimentales des Infections, Département des Maladies Infectieuses UFR de Médecine, 1, rue Gaston Veil, 44035 Nantes Cedex, France.
Biomed Res Int. 2013;2013:426709. doi: 10.1155/2013/426709. Epub 2013 Sep 4.
Tuberculosis (TB) is responsible for a high mortality rate (2.5%) worldwide, mainly in developing countries with a high prevalence of human immunodeficiency virus (HIV). The emergence of multiresistant strains of TB poses an extreme risk for TB outbreaks and highlights the need for global TB control strategies. Among Western African countries, Côte d'Ivoire (CI) represents a specific example of a country with great potential to prevent TB. Specifically, CI has a promising healthcare system for monitoring diseases, including vaccination programs. However, military and political conflict in CI favors the spread of infectious diseases, TB being among the most devastating. Compilation of the studies identifying common causes of TB would be extremely beneficial for the development of treatment and prevention strategies. Therefore, the purpose of this comprehensive review is to evaluate the epidemiology of TB in CI, describe the factors involved in pathogenesis, and suggest simple and applicable prevention strategies.
结核病（TB）在全球范围内导致高死亡率（2.5%），主要发生在艾滋病毒（HIV）高发的发展中国家。耐多药结核菌株的出现对结核病爆发构成了极端风险，凸显了制定全球结核病控制策略的必要性。在西非国家中，科特迪瓦（CI）是一个具有巨大潜力来预防结核病的国家的具体例子。具体而言，CI 拥有用于监测疾病（包括疫苗接种计划）的有前途的医疗保健系统。然而，CI 的军事和政治冲突有利于传染病的传播，结核病是其中最具破坏性的疾病之一。综合研究结核病的常见病因将非常有助于制定治疗和预防策略。因此，本综述的目的是评估 CI 结核病的流行病学，描述发病机制涉及的因素，并提出简单适用的预防策略。
