钯（II）催化的使用钾芳基三氟硼酸盐的苄基膦酸单酯的邻位芳基化反应。
Palladium(II)-catalyzed ortho-arylation of benzylic phosphonic monoesters using potassium aryltrifluoroborates.
机构信息
Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University , Singapore 637371, Singapore.
出版信息
J Org Chem. 2013 Nov 15;78(22):11247-54. doi: 10.1021/jo401716p. Epub 2013 Nov 1.
PMID:24093503
Abstract
The new monophosphonic acid directing group was successfully utilized in the Pd (II)-catalyzed ortho-arylation of benzylic phosphonic monoesters using potassium aryltrifluoroborates. A wide range of benzylic phosphonic monoesters underwent clean ortho-arylation in high yields, and excellent functional group tolerance was also observed.
摘要
新型单膦酸导向基团在钯（II）催化的使用钾芳基三氟硼酸盐的苄基膦酸单酯的邻位芳基化反应中得到了成功的应用。一系列的苄基膦酸单酯以高收率实现了清洁的邻位芳基化，同时还表现出了优异的官能团耐受性。
Zotero 插件