铱催化通过 C-H 硼化反应制备 SF5 取代的芳基三氟硼酸钾盐及其在铃木-宫浦反应中的应用。
Ir-catalyzed preparation of SF5-substituted potassium aryl trifluoroborates via C-H borylation and their application in the Suzuki-Miyaura reaction.
机构信息
Laboratory of Organic Chemistry, ETH-Zürich , HCI H335, Wolfgang-Pauli-Strasse 10, 8093 Zürich, Switzerland.
出版信息
Org Lett. 2013 Oct 18;15(20):5147-9. doi: 10.1021/ol4025666. Epub 2013 Oct 3.
PMID:24090251
Abstract
The preparation of new pentafluorosulfanyl-substituted potassium aryltrifluoroborates via Ir-catalyzed C-H borylation is reported. The utility of these novel building blocks was demonstrated in the Suzuki-Miyaura cross-coupling reaction, giving access to 3,5-disubstituted pentafluorosulfanylbenzenes.
摘要
本文报道了通过 Ir 催化的 C-H 硼化反应制备新型五氟硫基取代的钾芳基三氟硼酸盐。这些新型砌块在 Suzuki-Miyaura 交叉偶联反应中的应用得到了证明，可得到 3,5-二取代的五氟硫基苯。
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