Stereotactic and Radiation Neurosurgery, Na Homolce Hospital, Roentgenova 2, Prague 5, 150 30, Czech Republic.
Neurosurg Clin N Am. 2013 Oct;24(4):509-19. doi: 10.1016/j.nec.2013.05.005. Epub 2013 Jul 1.
The goal of pituitary adenoma radiosurgery is to halt tumor growth, normalize hormonal hypersecretion if present, maintain normal pituitary function, and preserve important structures around the sella. The radiation dose necessary to stop tumor growth is lower than the dose necessary to achieve normalization of hormonal hypersecretion. The minimum distance required between the irradiated target and the optic pathway should be 2 mm for secreting adenomas, but in cases of nonsecreting adenomas this distance is even lower. The current role of radiosurgery in most cases is as an adjuvant treatment of residual or recurrent adenomas after previous microsurgery.
垂体腺瘤放射外科的目标是阻止肿瘤生长，如果存在，使激素分泌过多正常化，维持正常的垂体功能，并保护鞍区周围的重要结构。停止肿瘤生长所需的辐射剂量低于使激素分泌过多正常化所需的剂量。接受照射的靶标与视觉通路之间所需的最小距离应为 2 毫米，用于分泌性腺瘤，但对于非分泌性腺瘤，这个距离甚至更低。放射外科在大多数情况下的作用是作为先前微创手术后残留或复发性腺瘤的辅助治疗。
