Beijing National Laboratory for Molecular Sciences (BNLMS), CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences , Beijing 100190, China.
J Org Chem. 2013 Nov 1;78(21):11076-81. doi: 10.1021/jo4016419. Epub 2013 Oct 24.
The reaction of Morita-Baylis-Hillman (MBH) alcohols with Me2PhSiBpin under the catalysis of Cu(OTf)2/pyridine in methanol has been developed. The direct silylation of allylic alcohols via dual activation of the Si-B bond and the hydroxyl group of the MBH alcohol provides an efficient and convenient method for the synthesis of functionalized allylsilanes.
发展了在甲醇中，在 Cu(OTf)2/吡啶的催化下，Morita-Baylis-Hillman (MBH) 醇与 Me2PhSiBpin 的反应。通过 Si-B 键和 MBH 醇的羟基的双重活化，实现了烯丙醇的直接硅烷化，为功能化烯丙基硅烷的合成提供了一种高效、便捷的方法。
