Eubanks Jason David, Belding Jon, Schnaser Erik, Rowan Andrew, Moffitt Gable, Weaver John, Reich Michael S, Bechtel Chris, Xie Ke, Gande Abhiram, Hohl Justin, Braly Brett, Hilibrand Alan, Kang James D
Orthopedics. 2013 Oct 1;36(10):e1251-5. doi: 10.3928/01477447-20130920-15.
Symptomatic adjacent segment disease (ASD) after anterior cervical fusion (ACF) is reported in 25% of patients at 10 years postoperatively. Debate continues as to whether this degeneration is due to the natural history of the disk or the changed biomechanics after ACF. This study explored whether congenital stenosis predisposes patients to an increased incidence of ASD after ACF. A retrospective review of 635 patients with myelopathy or radiculopathy was performed; 364 patients had complete records for review. Patients underwent 1- to 5-level ACF (94 one-level, 145 two-level, 79 three-level, 45 four-level, and 1 five-level). Radiographs were evaluated for bony congenital stenosis using validated parameters, and ASD was measured according to Hilibrand's criteria and correlated with symptomatic ASD. Congenital stenosis was found in 21.7% of patients and radiographic ASD in 33.5%, with a significant association between these parameters. However, symptomatic ASD occurred in 11.8% of patients; no association between congenital stenosis and symptomatic ASD or myelopathy and ASD was found. Clinical results demonstrated excellent or good Robinson scores in 86.2% of patients and Odom scores in 87% of patients. Despite mostly excellent to good outcomes, symptomatic ASD is common after ACF. Although congenital stenosis appears to increase the incidence of radiographic ASD, it does not appear to predict symptomatic ASD.
据报道,颈椎前路融合术(ACF)后出现症状性相邻节段疾病(ASD)的患者在术后10年时占25%。关于这种退变是由于椎间盘的自然病程还是ACF后生物力学改变所致,仍存在争议。本研究探讨先天性狭窄是否使患者在ACF后发生ASD的几率增加。对635例患有脊髓病或神经根病的患者进行了回顾性研究;364例患者有完整记录可供审查。患者接受了1至5节段的ACF(94例单节段、145例双节段、79例三节段、45例四节段和1例五节段)。使用经过验证的参数对X线片进行先天性骨狭窄评估,并根据希利布兰德标准测量ASD,并将其与症状性ASD相关联。21.7%的患者存在先天性狭窄,33.5%的患者存在影像学ASD,这些参数之间存在显著关联。然而,11.8%的患者出现症状性ASD;未发现先天性狭窄与症状性ASD之间或脊髓病与ASD之间存在关联。临床结果显示,86.2%的患者罗宾逊评分优秀或良好,87%的患者奥多姆评分优秀或良好。尽管大多数患者预后大多良好,但ACF后症状性ASD很常见。虽然先天性狭窄似乎会增加影像学ASD的发生率,但它似乎并不能预测症状性ASD。