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迈向建立全球诱导多能干细胞库。

Toward the development of a global induced pluripotent stem cell library.

机构信息

Medical Director, SNBTS HeadQuarters, 21 Ellen's Glen Road, Edinburgh EH17 7QT, UK.

出版信息

Cell Stem Cell. 2013 Oct 3;13(4):382-4. doi: 10.1016/j.stem.2013.08.003.

DOI:10.1016/j.stem.2013.08.003
PMID:24094319
Abstract

The ability to preselect the donor genotype of iPSC lines provides important opportunities for immune matching in cell therapy. Here we propose that an international assessment should be made of how immune incompatibility can best be managed and how a network of GMP HLA homozygous haplobanks could be operated.

摘要

预先选择 iPSC 系供体基因型的能力为细胞治疗中的免疫匹配提供了重要机会。在这里，我们建议应该对如何最好地管理免疫不相容性以及如何运作 GMP HLA 纯合单倍型库网络进行国际评估。

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Cell Stem Cell. 2013 Oct 3;13(4):382-4. doi: 10.1016/j.stem.2013.08.003.
2
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Public Cord Blood Banks as a source of starting material for clinical grade HLA-homozygous induced pluripotent stem cells.公共脐带血库作为临床级 HLA 纯合诱导多能干细胞起始材料的来源。
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