Roth A, Kolarić K
Oncology. 1985;42(4):248-52. doi: 10.1159/000226040.
Cis-platinum, vinblastine, bleomycin and actinomycin D were used in the treatment of 24 patients with advanced testicular tumors. There were 8 seminomas and 16 nonseminomas. 19 patients were in stage III B, 2 in stage III A and 3 in stage II B. 7 patients were previously treated. Complete remission was obtained in 12 patients (50%), partial remission in 8 (33%) and treatment failed in 4 (16.7%). According to localization of metastases best results were obtained in patients with lung metastases (11 complete remissions out of 16 patients). Nausea, vomiting and alopecia were the most frequent toxic side effects of treatment. The authors hope that the 9 patients who are still in complete remission have good chances for complete recovery.
顺铂、长春花碱、博来霉素和放线菌素D用于治疗24例晚期睾丸肿瘤患者。其中精原细胞瘤8例，非精原细胞瘤16例。19例为ⅢB期，2例为ⅢA期，3例为ⅡB期。7例患者曾接受过治疗。12例患者（50%）获得完全缓解，8例（33%）部分缓解，4例（16.7%）治疗失败。根据转移灶的部位，肺转移患者取得了最佳疗效（16例患者中有11例完全缓解）。恶心、呕吐和脱发是治疗最常见的毒副作用。作者希望仍处于完全缓解状态的9例患者有完全康复的良好机会。
