Key Laboratory of Marine Medicine, Ministry of Education of China, School of Medicine and Pharmacy, Ocean University of China, Qingdao, 266003 Shandong, China.
Carbohydr Res. 2013 Nov 15;381:101-11. doi: 10.1016/j.carres.2013.08.005. Epub 2013 Aug 19.
A series of novel glycosyl allenoates were prepared by condensions of hemiacetals with 3,3-dimethyl-4,5-allenoic acid. Their glycosylations with various alcohols under the promotion of bromodimethylsulfonium bromide/silver triflate smoothly proceeded to produce disaccharides. Studies reveal that allenic group is crucial for the efficient glylcosylation of glycosyl allenoate.
通过半缩醛与 3,3-二甲基-4,5-烯酸的缩合反应，制备了一系列新型的糖基烯丙酯。在溴二甲亚砜/三氟甲磺酸银的促进下，它们与各种醇的糖苷化反应顺利进行，生成二糖。研究表明，烯丙基对于糖基烯丙酯的高效糖苷化反应至关重要。
