Thoenen H, Edgar D
Science. 1985 Jul 19;229(4710):238-42. doi: 10.1126/science.2409599.
In addition to nerve growth factor (NGF), many proteins present in soluble tissue extracts and in the extracellular matrix influence the survival and development of cultured neurons. The structure, synthesis, and mechanism of action of NGF as a neurotrophic factor are considered along with the experiments on the new putative trophic molecules.
除了神经生长因子(NGF)外,可溶性组织提取物和细胞外基质中存在的许多蛋白质都会影响培养神经元的存活和发育。本文将结合有关新的假定营养分子的实验,探讨NGF作为一种神经营养因子的结构、合成及作用机制。