Kon Graversen Veronica A, Jampol Lee M, Meredith Travis, Landers Maurice, Slakter Jason, Brucker Alexander J, Rabb Maurice
*Department of Ophthalmology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; †Deceased; ‡Department of Ophthalmology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois; §Vitreous-Retina-Macula Consultants of New York, New York, New York; and ¶Department of Ophthalmology, Scheie Eye Institute, Philadelphia, Pennsylvania.
Retina. 2014 Mar;34(3):483-9. doi: 10.1097/IAE.0b013e3182a48759.
To evaluate the possible etiologies of a hemorrhagic unilateral retinopathy in healthy patients.
Retrospective case series and review of the literature. All patients underwent a detailed ophthalmologic evaluation and analyses of their medical histories.
Eleven eyes of 10 patients with unexplained unilateral, predominantly deep, intraretinal hemorrhages were identified. All patients were women. Mean age of the subjects was 48.4 years (range, 25-83 years). The main complaint at presentation was sudden visual loss, with visual acuity ranging from 20/20 to hand motion. The mean follow-up was 17 months, and the 9 eyes with follow-up showed spontaneous resolution of the hemorrhages and marked improvement of vision. There was no history of Valsalva maneuver or strenuous exercise. The patients were healthy at presentation and during follow-ups as long as 84 months.
This series depicts the characteristics of a possible new entity with a review of the differential diagnosis. The visual outcome was excellent.
评估健康患者单侧出血性视网膜病变的可能病因。
回顾性病例系列研究及文献综述。所有患者均接受了详细的眼科评估并分析其病史。
确定了10例不明原因单侧、主要为深层视网膜内出血患者的11只眼。所有患者均为女性。受试者的平均年龄为48.4岁（范围25 - 83岁）。就诊时的主要症状为突发视力丧失，视力范围从20/20到手动。平均随访17个月，9只有随访结果的眼睛显示出血自发吸收且视力显著改善。无瓦尔萨尔瓦动作或剧烈运动史。患者在就诊时及长达84个月的随访期间均健康。
本系列研究描述了一种可能的新疾病实体的特征，并对鉴别诊断进行了综述。视觉预后良好。
